Dissolvable Film Format Evolves to Buccal Drug Delivery Applications

5/7/14

Dissolvable Film Format Evolves to Buccal Drug Delivery Applications
Drug, Development & Delivery
By: Scott Barnhart

Dissolvable oral thin films (OTFs) are a proven technology for the systemic delivery of active pharmaceutical ingredients (APIs) and have been adopted as a practical alternative oral dosage format for over-the-counter and prescription drugs. The chemistry and art behind formulating drug-loaded films for buccal applications draws upon formulation expertise derived from traditional OTFs for GI delivery and from transdermal dosage forms. Through an extensive understanding of these dosage forms and by leveraging their similarities, formulators can effectively tailor a dissolvable film platform to add therapeutic value for delivering drug compounds through the oral mucosa. 

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