The Growing Importance Of Release Liners In Pharmaceutical Manufacturing


By: Martha Sloboda
Pharmaceutical Technology Europe, Feb 2011

Manufacturers across the pharmaceutical industry employ a variety of techniques to create safe, efficacious products. Frequently, processing aids are employed to help maintain the integrity of the dosage form during manufacturing. Release liners frequently serve as both processing aids and final components in transdermal patch systems. Typically, release liners are a silicone coated polyester or paper product, and their value and use for transdermal patch systems are well understood. This article discusses the chemistry and benefits of release liners as a processing aid and as a component for liquid cast dosage forms.